Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression - PubMed
Tumor-associated macrophages (TAMs) have been shown to be associated with poor prognosis of cancer and are predominately localized in the hypoxia regions of tumor. We demonstrated in this study that hypoxia increases the synthesis and secretion of galectin-3 by TAMs. The increased expression of gale …