2016

Implications for the Multi-Axis Metabolic Trap

Learn the most common causes of high blood pressure and how to lower it naturally through vitamins, minerals, exercise, sleep, and anti-inflammatory habits.

One of the most consistent findings in brain health research is that our brains and by extension their health are majorly impacted by our lives. The brain is exquisitely sensitive to its environment, what you eat, how you sleep, how much you move, how stressed you are. But a compelling and underappreciated line of research is now asking a different kind of question: what about what you believe? Specifically, could your brain beliefs change how it ages?

Atrazine is a Dangerous Pesticide Highlighted in Theo Colburn's Book, Our Stolen Future.

To rotate or not; that is the question?

Background/Objectives: Marine-derived bioactive compounds have attracted increasing interest due to their potential antiviral properties. This study investigated in vitro antiviral activity of oil extracted from the green-lipped mussel (Perna canaliculus, GLM) and low-molecular-weight (LMW) fucoidan from Undaria pinnatifida against three human viruses in mammalian cell systems. herpes simplex virus-1 (HSV-1), respiratory syncytial virus (RSV), and SARS-CoV-2. These marine compounds were selected with the longer-term aim of evaluating their combination as a potential synergistic antiviral strategy. Methods: Antiviral efficacy was assessed using complementary assay platforms, including plaque reduction assays in mammalian cell systems and a lentiviral pseudovirus system delivering a bioluminescent reporter gene in HEK293/ACE2 cells pseudotyped with the SARS-CoV-2 spike glycoprotein. Cytotoxicity was assessed in parallel, and the selectivity index (SI) was calculated as the ratio of CC50 to IC50 for each compound and virus tested. Results: GLM oil showed potential antiviral activity against SARS-CoV-2 pseudovirus (SI > 6.20), with limited activity against RSV (SI > 3.48) and HSV-1 (SI > 2.28). In contrast, LMW fucoidan did not demonstrate antiviral activity against any of the tested viruses. Conclusions: These findings support further investigation of GLM-derived bioactive compounds as potential antiviral agents, including studies to elucidate their mechanisms of action and in vivo studies to confirm their antiviral efficacy. Combination studies were not pursued in the present work as both compounds require further optimisation individually; however, future studies should evaluate their combined antiviral potential, as synergistic or additive effects remain plausible.

Fucoidan is a polysaccharide bioactive compound, mainly from brown algae, characterized by multiple biological activities, including...

To rotate or not rotate, that is the question!

Not all forms of vitamin B12 are created equal. Learn more about which ones are best and which should be avoided at all costs.

I asked Claude Opus 4.7 to analyze the data because no public health official wants to know the numbers of COVID vaccine injured. Here are the results of that analysis.

The Skin of an Orange

A team of named, persistent AI staff that work in parallel, produce real output, and run on a schedule. Not another chatbot.

Does Israel need complete peace before the Gog and Magog war begins...

Mannatech’s vegan, plant-based supplement, Ambrotose Complex, elevates your self-care regimen to help you get closer to feeling and looking your best.