A recent analysis of participants in the FINGER study tracked about 600 people (average age around 69) for 2 years. Those with better muscle strength and function at the start of the study as measured through tests like grip strength and chair stand had better global cognition, memory, and executive function at the end after correcting for variables like age and comorbidities. However, in some recent publications, there’s a signal that building leg muscle may be especially key to brain health.

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But a major new study in the journal Science provides some of the strongest evidence yet that we continue to make new neurons into adulthood — particularly in a memory-critical part of the brain called the hippocampus. This finding not only shifts a century-old perspective on human brain biology but also opens exciting possibilities for enhancing brain health across the lifespan.

Indeed, some recent research suggests that improvements in memory from cognitive training are driven by increases in BDNF, and it may also be the case that part of the benefit provided to people from antidepressants is through BDNF increases. The good news is that independent of pharmaceuticals, research suggests basic lifestyle changes can increase BDNF levels

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Is it possible for a single treatment to reset the brain from years of trauma, addiction, and injury? For decades, this sounded like science fiction. Today, ...

From creatine to magnesium, specific nutrients appear to influence inflammation, synaptic plasticity, and even structural integrity of brain tissue, and may ...

This article reviews the latest science on clinically studied dietary nutrients that may help aid in slowing brain aging and protecting our brain function over our lives.

Background: Neurodegenerative diseases (NDDs) are multifactorial disorders frequently associated with gut dysbiosis, oxidative stress, and inflammation; however, the pathophysiological mechanisms remain poorly understood. Methods: Using untargeted mass spectrometry-based metabolomics a …

Earlier laboratory-based evidence has suggested that polyphenol-rich, decaffeinated whole coffee cherry extract (CCE) supports improvements in acute and long-term cognitive performance. To better understand CCE's potential to promote cognitive processing, we conducted a first-of-its-kind remote clin …

Objectives: Brain-derived neurotrophic factor (BDNF) plays an essential role in brain and metabolic health. The fact that higher concentrations are associated with improved cognitive performance has resulted in numerous intervention trials that aim at elevating BDNF levels. This systematic re …

(NaturalHealth365) Recent research reveals Bacopa monnieri extract improves brain health - memory, concentration, and sleep quality.

Creatine may boost brain metabolic and immune systems. This is cutting-edge research worth knowing! For all the references/articles I cited: https://www.aust...

The decades of evidence showing DMSO revolutionizes the care of many "untreatable" circulatory and neurologic conditions.

(NaturalHealth365) Green leafy vegetables can slow down cognitive decline by more than a decade. Learn which ones are the best.

How Strength Training Boosts the Brain Get my Free Guide: 11 Science-Backed Steps to Help Boost Memory and Prevent Dementia https://www.austinperlmutter.com/memoryguide Full blog: https://www.austinperlmutter.com/post/how-weightlifting-boosts-your-brain Regular exercise lowers the risk of brain issues like depression and Alzheimer’s disease. Resistance training should also be considered for its brain health benefits. Benefits of Strength Training for Brain Health: 1. Better brain health in those who engage in resistance training. 2. Improved brain function, particularly in the elderly, from starting weightlifting. 3. Cognitive improvements in people with cognitive decline after resistance training. 4. Decreased depressive symptoms observed through resistance training. 5. Regulation of Metabolic Balance and Immunity seem to be key Tips for Effective Resistance Training: Start light and gradually increase weight. Consider working with a trainer for guidance. Group classes can boost motivation and provide social benefits. Resistance bands offer a versatile and effective alternative. Pay attention to your body to avoid injuries. Include leg exercises for maximum benefit. Ensure adequate protein intake and consider creatine supplementation for muscle and brain health. Check out my newsletter! https://www.austinperlmutter.com/newsletter This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment. #exercise #weightlifting #neuroscience

Please subscribe to my channel! Creatine May Have Brain and Muscle Benefits: Initially popular among athletes for muscle growth and performance, creatine is ...

From metabolic to anti-inflammatory benefits, muscle health matters for brain health

From metabolic boosts to anti-inflammatory effects and neuroplasticity, here's why muscle health matters for brain health, and how to prioritize it.Full blog...

(NaturalHealth365) Discover how regular exercise can positively impact the immune system and promote the growth of new brain cells.

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(NaturalHealth365) New research reveals a startling link between those nagging headaches and inflammation. Learn what researchers found.

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5 Key learnings from 2023 By Austin Perlmutter, MD Over the last several days, I had the honor of attending and presenting at the annual Personalized Lifestyle Medicine Institute Conference. This year’s theme was “neuroimmunity,” which meant the focus was squarely on brain health. Speakers at the conference included some of the world’s leading researchers and clinicians on the brain, and the presentations were nothing short of outstanding. I’d like to share with you 5 of the top predictions for

This research is literally mind-bending By Austin Perlmutter, MD KEY POINTS: How Psychedelics May Impact the Brain Influence on Neurotransmitters and Receptors: Psychedelics have a significant impact on neurotransmitters, with the serotonin receptor 2A playing a central role. They can also affect other neurotransmitters like GABA, dopamine, norepinephrine, and glutamate. Changes in Brain Activation Patterns: Psychedelics alter brain activation patterns, particularly in the default mode network (