New therapy has already proven successful in dogs

Do you want to know how to make ozone eye drops? We'll give you a step-by-step procedure on how to prepare a batch in this blog post.

Higher dietary intake of vitamin C has been found to have a potentially preventative effect on cataract progression in the first twin study of cataracts to examine to what degree genetic and environmental factors influence their progression with age.

Exploring the genetic basis of congenital cataracts in two families identifies a molecule, lanosterol, which prevents intracellular protein aggregation of various cataract-causing mutant crystallins, and which can reduce cataract severity and increase lens transparency in vivo in dogs.

The medicinal plants are widely recommended worldwide by the traditional and modern medical practitioners for curing various diseases of patients. Aloe vera is well known for its considerable medicinal properties. Aloe is widely used in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from X-rays, lung cancer, intestinal problems, increasing High Density Lipoprotein (HDL), reducing Low Density Lipoprotein (LDL), reducing blood sugar in Diabetics, fighting against Acquired Immuno Deficiency Syndrome (AIDS), allergies and improving immune system. Aloe is used in traditional Indian medicine for constipation, colic, skin diseases, worm infestation, and infections. It is found in variety of commercial products such as, pills, sprays, ointments, lotions, liquids, drinks, jellies and creams. All these uses associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. The chemistry of the plant has revealed that there are more than 200 different biologically active substances.

Discover top natural remedies to help cataracts and reduce cataract symptoms with remedies such as ALA, phytonutrients, and lutein.

Researchers have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

As the years progress, you might find yourself seeking out treatment of cataracts more and more. Check out this post to learn some contemporary treatments!

The age-dependent loss of solubility and aggregation of crystallins constitute the pathological hallmarks of cataract. Several biochemical and biophysical factors are responsible for the reduction of crystallins’ solubility and formation of irreversible protein aggregates, which display amyloid-like characteristics. The present study reports the heat-induced aggregation of soluble proteins isolated from human cataract lenses and the formation of amyloid-like structures. Exposure of protein at 55 °C for 4 h resulted in extensive (≈ 60%) protein aggregation. The heat-induced protein aggregates displayed substantial (≈ 20 nm) redshift in the wavelength of maximum absorption (λmax) of Congo red (CR) and increase in Thioflavin T (ThT) fluorescence emission intensity, indicating the presence of amyloid-like structures in the heat-induced protein aggregates. Subsequently, the addition of trehalose resulted in substantial inhibition of heat-induced aggregation and the formation of amyloid-like structure. The ability of trehalose to inhibit the heat-induced aggregation was found to be linearly dependent upon its concentration used. The optimum effect was observed in the presence of 30–40% (w/v) trehalose where the aggregated was found to be reduced from 60 to 30%. The present study demonstrated the ability to trehalose to inhibit the protein aggregation and interfere with the formation of amyloid-like structures.

Purpose Prospective, randomised, open-label, comparative study to evaluate efficacy of trehalose/sodium hyaluronate eye drops for post-operative discomfort and tear film stability in patients undergoing cataract surgery. Methods Patients with healthy ocular surface, subclinical, or mild dry eye were enrolled. Tear breakup time (TBUT), Schirmer test, dry eye symptoms, corneal fluorescein staining (CFS), and ocular surface disease (OSDI) evaluation were performed pre-operatively and at two and four weeks after surgery. Patients were assigned to receive trehalose/sodium hyaluronate eye drops b.i.d (Group A), or 0.9% unpreserved sodium chloride eye drops b.i.d for 4 weeks (Group B). Results One hundred and thirty-five patients were randomised, 66 patients in Group A (73.2 ± 4.5 years) and 69 patients in Group B (74.3 ± 3.8 years), 60.8% females. Fifteen patients (8 Group A) were lost at follow-up. Pre-operatively, no between-group differences were observed, and TBUT increased in Group A between the pre-operative and 2 and 4 week evaluations and was higher in group A than in Group B at 4 weeks. Schirmer test and CFS showed an improvement only in Group A four weeks post-operatively. In Group A an improvement was observed after two and four weeks in foreign body and puncture sensation, whilst a difference in blinking discomfort was observed after four weeks. In Group B we observed an improvement in puncture sensation two and four weeks after surgery. Mean OSDI scores differences between the two groups were significant at four weeks. Conclusions Trehalose/sodium hyaluronate eye drops were effective in reducing signs and symptoms of dry eye and improving tear film stability

Conjunctivitis, keratoconjunctivitis, and corneal ulcers are common eye disorders frequently diagnosed in both humans and animals, and are currently treated by topical administration of eye drops containing anti-inflammatory and antibacterial agents. ...

Trehalose, a non-reducing disaccharide, induces autophagy. Trehalose mitigates insulin resistance and adipocyte hypertrophy in obese mice; however, it…

Fucoidans have been reported to exert anticancer effects with simultaneous low toxicity against healthy tissue. That correlation was observed in several cancer models, however, it has never been investigated in head and neck cancer before. To magnify the efficacy of conventional therapy, the adminis …

The present study was undertaken to evaluate the protective effect of aqueous leaf extract of Aloe vera (ALEAV) in animal model (wistar albino rats) through macroscopic and histopathological study of the colon after inducing ulcerative colitis by usage of acetic acid. 30 healthy albino rats of either sex 150-200g body wt. and 2-4 months age groups were divided into five groups (six in each). Group 1 was normal control group receiving vehicle 1ml of normal saline transrectally (negative control). Group 2 was ulcerative colitis control which was treated with normal saline. Group 3 & 4 were administered aqueous leaf extract of Aloe vera suspension(test drug) 150,300mg/kg bodyweight dose orally for 10 days respectively. Ulcerative colitis was induced on 10 th day. Group 5 was administered prednisolone(1mg/kg) orally for 3 days. On the 3 rd day ulcerative colitis was induced by transrectal administration of 1 ml of 4% acetic acid solution. In all the groups, animals were observed for decrease in bodyweight, stool consistency and rectal bleeding i.e Disease Activity Index for 48 hours after inducing ulcerative colitis. After 48 hours the rats were sacrificed by high dose of ether anaesthesia and a piece of colonic segment(10cm in length) were resected out and subjected to macroscopical study(colon mucosal index) and microscopic evaluation. ALEAV at 150 mg/kg produced significant improvement in macroscopic score in comparison to disease control (group 2) which is comparable to that of normal control (group 1) in ulcerative colitis model. Histopathological studies showed significant dose dependent decrease in lymphoid hyperplasia, neutrophilic infiltration, crypt damage and submucosal inflammation in ALEAV treated group (150 and 300 mg/kg b.w) in comparison to disease control.

Fucoidan is a bio-functional polysaccharide, mainly reported in brown seaweed. Diverse potential of fucoidan has created intense interest to review th…

Fucoidan, a sulfated polysaccharide extracted from brown seaweeds, possesses many biological activities including anti-inflammatory and antioxidant ac…

The present study demonstrated that fucoidan could inhibit the in vitro progression of oral squamous cell carcinoma (OSCC) cells by mediating the level of circFLNA. CircFLNA effects on signaling path...

Fucoidans (FUCs) are sulfated polysaccharides that have a wide range of bioactivities. The current study was designed to evaluate the antioxidant potential of FUC against microcystin-LR (MC-LR)-induced toxicity. Five mice groups (n = 8) were used. Group 1 received saline, Group 2 received oral FUC 1 …

Fucoidan is a functional food that possesses various biological activities. This study aims to determine the effects of fucoidan from Undaria pinnatif…