2016

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OmegaXL
OmegaXL
OmegaXL is a powerful natural supplement shown in clinical research to support joint comfort and function? It contains more than 30 healthy fatty acids, including DHA and EPA. Give it a try, OmegaXL works!
·omegaxl.com·
OmegaXL
Parkinson’s Disease Education - YouTube
Parkinson’s Disease Education - YouTube
This channel is dedicated to helping Persons with Parkinson's Disease to become Parkinson's Warriors fighting their disease wielding the weapon of knowledge about PD and the impact that it has on daily living. Book 1:1 consultation with a Parkinson's Disease Expert here: https://clarity.fm/pdeducation Explore channel memberships here: YouTube: https://www.youtube.com/channel/UC0g3abv8hkaqZbGD8y1dfYQ/join Patreon: https://www.patreon.com/pdeducation If you have products that you would like for me to review on the channel please send them here: Parkinson's Disease Education P.O. Box 1678 Broken Arrow, OK 74013
·youtube.com·
Parkinson’s Disease Education - YouTube
! ! Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? | Journal of Neurology
! ! Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? | Journal of Neurology
Following reports of low striatal dopamine content in Parkinson’s disease, levodopa was shown to rapidly reverse hypokinesis, establishing the model of disease as one of dopamine deficiency. Dopaminergic therapy became standard of care, yet it failed to reverse the disease, suggesting the understanding of disease was incomplete. The literature suggests the potential for toxicity of dopamine and its metabolites, perhaps more relevant given the recent evidence for elevated cytosolic dopamine levels in the dopaminergic neurons of people with Parkinson’s. To understand the relevance of these data, multiple investigations are reviewed that tested dopamine reduction therapy as an alternative to dopaminergic agents. The data from use of an inhibitor of dopamine synthesis in experimental models suggest that such an approach could reverse disease pathology, which suggests that cytosolic dopamine excess is a primary driver of disease. These data support clinical investigation of dopamine reduction therapy for Parkinson’s disease. Doing so will determine whether these experimental models are predictive and this treatment strategy is worth pursuing further. If clinical data are positive, it could warrant reconsideration of our disease model and treatment strategies, including a shift from dopaminergic to dopamine reduction treatment of the disease.
·link.springer.com·
! ! Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? | Journal of Neurology
! ! Right Brain Bio
! ! Right Brain Bio
Right Brain Bio is developing a data-driven treatment for Parkinson's - one so revolutionary that it will transform disease understanding and treatment.
·rightbrainbio.com·
! ! Right Brain Bio
Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease: A randomized, double‐blind, placebo‐controlled, crossover study, with an open‐label extension - PMC
Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease: A randomized, double‐blind, placebo‐controlled, crossover study, with an open‐label extension - PMC
Cerebral glucose and insulin metabolism is impaired in Alzheimer's disease (AD). Ketones provide alternative energy. Will medium chain triglyceride (MCT) oil, a nutritional source of ketones, impact cognition in AD? This was a 6‐month randomized, ...
·pmc.ncbi.nlm.nih.gov·
Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease: A randomized, double‐blind, placebo‐controlled, crossover study, with an open‐label extension - PMC
The Silent Killer in Your Kitchen! - YouTube
The Silent Killer in Your Kitchen! - YouTube
In this video, Dr. Nathan Bryan debunks the outdated belief that fats cause heart disease, emphasizing that fats are essential for brain function, cell membr...
·youtube.com·
The Silent Killer in Your Kitchen! - YouTube
Association between increased and decreased gut microbiota abundance and Parkinson's disease: A systematic review and subgroup meta-analysis - PubMed
Association between increased and decreased gut microbiota abundance and Parkinson's disease: A systematic review and subgroup meta-analysis - PubMed
Patients in the PD cohort exhibited distinctive microbiota compositions compared to healthy individuals, with unique differential patterns in gut microbiome abundance at the phylum, family, and genus levels that may be associated wtih PD pathogenesis.
·pubmed.ncbi.nlm.nih.gov·
Association between increased and decreased gut microbiota abundance and Parkinson's disease: A systematic review and subgroup meta-analysis - PubMed
Literature review and meta-analysis of environmental toxins associated with increased risk of Parkinson's disease - PubMed
Literature review and meta-analysis of environmental toxins associated with increased risk of Parkinson's disease - PubMed
Parkinson's disease (PD) is a neurodegenerative disorder and leading cause of death worldwide, whose pathogenesis has been linked to toxic environmental exposures. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (i) to compile, and group by exposure …
·pubmed.ncbi.nlm.nih.gov·
Literature review and meta-analysis of environmental toxins associated with increased risk of Parkinson's disease - PubMed
Mitochondrial Dysfunction in Genetic and Non-Genetic Parkinson's Disease - PubMed
Mitochondrial Dysfunction in Genetic and Non-Genetic Parkinson's Disease - PubMed
Mitochondrial dysfunction is a hallmark of Parkinson's disease (PD) pathogenesis, contributing to increased oxidative stress and impaired endo-lysosomal-proteasome system efficiency underlying neuronal injury. Genetic studies have identified 19 monogenic mutations-accounting for ~10% of PD cases-tha …
·pubmed.ncbi.nlm.nih.gov·
Mitochondrial Dysfunction in Genetic and Non-Genetic Parkinson's Disease - PubMed