OmegaXL is a powerful natural supplement shown in clinical research to support joint comfort and function? It contains more than 30 healthy fatty acids, including DHA and EPA. Give it a try, OmegaXL works!
! ! Science of Ketosis: Regain Your Metabolic Health & Age Backwards | Dr. Dominic D’Agostino - YouTube
🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱The ketogenic d...
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(PDF) Low Dose Alpha-Methyl-Para-Tyrosine (AMPT) in the Treatment of Dystonia and Dyskinesia
PDF | AMPT (alpha-methyl-para-tyrosine) is an inhibitor of tyrosine hydroxylase, the rate-limiting enzyme in dopamine biosynthesis. In clinical... | Find, read and cite all the research you need on ResearchGate
Seizures and epilepsy (mechanism of disease) - YouTube
This is a flowchart on seizures and epilepsy, covering the etiology, pathophysiology, and manifestations. ADDITIONAL TAGS: Atonic seizure ("drop attack"):Non...
! ! Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? | Journal of Neurology
Following reports of low striatal dopamine content in Parkinson’s disease, levodopa was shown to rapidly reverse hypokinesis, establishing the model of disease as one of dopamine deficiency. Dopaminergic therapy became standard of care, yet it failed to reverse the disease, suggesting the understanding of disease was incomplete. The literature suggests the potential for toxicity of dopamine and its metabolites, perhaps more relevant given the recent evidence for elevated cytosolic dopamine levels in the dopaminergic neurons of people with Parkinson’s. To understand the relevance of these data, multiple investigations are reviewed that tested dopamine reduction therapy as an alternative to dopaminergic agents. The data from use of an inhibitor of dopamine synthesis in experimental models suggest that such an approach could reverse disease pathology, which suggests that cytosolic dopamine excess is a primary driver of disease. These data support clinical investigation of dopamine reduction therapy for Parkinson’s disease. Doing so will determine whether these experimental models are predictive and this treatment strategy is worth pursuing further. If clinical data are positive, it could warrant reconsideration of our disease model and treatment strategies, including a shift from dopaminergic to dopamine reduction treatment of the disease.
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Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease: A randomized, double‐blind, placebo‐controlled, crossover study, with an open‐label extension - PMC
Cerebral glucose and insulin metabolism is impaired in Alzheimer's disease (AD). Ketones provide alternative energy. Will medium chain triglyceride (MCT) oil, a nutritional source of ketones, impact cognition in AD? This was a 6‐month randomized, ...
Trump Gave ULTIMATUM to ISRAEL: Enforcing DAN 9:27 Covenant? - YouTube
Trump just gave an ultimatum to Israel to agree to divide the Land of Israel in a two-state solution. Is this the enforcing of the Dan 9:27 Covenant? Is this...
Jesus gave 7 Critical Warnings to the Church in the Book of Revelation, and they are desperately needed for the present Last-Days Church. but some of the mai...
In this video, Dr. Nathan Bryan debunks the outdated belief that fats cause heart disease, emphasizing that fats are essential for brain function, cell membr...
Association between increased and decreased gut microbiota abundance and Parkinson's disease: A systematic review and subgroup meta-analysis - PubMed
Patients in the PD cohort exhibited distinctive microbiota compositions compared to healthy individuals, with unique differential patterns in gut microbiome abundance at the phylum, family, and genus levels that may be associated wtih PD pathogenesis.
Literature review and meta-analysis of environmental toxins associated with increased risk of Parkinson's disease - PubMed
Parkinson's disease (PD) is a neurodegenerative disorder and leading cause of death worldwide, whose pathogenesis has been linked to toxic environmental exposures. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (i) to compile, and group by exposure …
Mitochondrial Dysfunction in Genetic and Non-Genetic Parkinson's Disease - PubMed
Mitochondrial dysfunction is a hallmark of Parkinson's disease (PD) pathogenesis, contributing to increased oxidative stress and impaired endo-lysosomal-proteasome system efficiency underlying neuronal injury. Genetic studies have identified 19 monogenic mutations-accounting for ~10% of PD cases-tha …