2016

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism has been implicated as a potential risk factor for epilepsy. To date, many case–control studies have investigated the association between MTHFR C677T polymorphism and epilepsy susceptibility. However, those findings were inconsistent. The objective of this study is to evaluate the precise association between MTHFR C677T polymorphism and epilepsy.

Learn about the four different ketogenic diet therapies for childhood epilepsy, which may be tried when medication has failed to control seizures and surgery is not an option.

The term epilepsy is collectively designated for a group of chronic central nervous system disorders characterized by spontaneous occurrence of seizures generally associated with the loss of consciousness and body movements (convulsions). Anticonvulsant drugs are used to control the convulsions by inhibiting the discharge and then producing hypnosis. Various synthetic drugs, viz. phenytoin (PHT), diazepam, valproate (VPA), leviteracetam, etc., are used for the treatment. These agents have a new spectrum of efficacy and novel adverse effects. They also represent an enormous escalation of costs. At present, herbal therapies are tried by patients in developing as well as developed countries for control of seizures or adverse effects from antiepileptic drugs, or for general health maintenance. There are number of synthetic drugs available for treatment of epilepsy in modern therapy, but the major disadvantage being faced is their chronic side effects. Treatment of epilepsy with herbal drugs as adjuvant seems to be more beneficial and is gaining more popularity due to their fewer side effects.

Learn about medical cannabis in the treatment of seizures, including the latest research, laws, and advocacy efforts.

Methylfolate side effects are significant. Learn about methylfolate side effects and how to stop them. Methylfolate side effects can be stopped quickly.

Methylenetetrahydrofolate reductase (MTHFR) is one of the most important enzymes in human physiology, having influence on at least as many biochemical processes as it has syllables in its name. Deficiencies in this enzyme increase the risk of CVD, several types of cancer, congenital defects, and inflammatory bowel disease. Fortunately, deficiencies are correctable with targeted supplementation.

MTHFR gene mutations can cause absolutely no symptoms at all. They may also increase susceptibility to severe health conditions. Research is still pending on which medical conditions are caused by, or at least partially attributed to, the MTHFR gene mutations. I actually don’t think any of these are actually caused by MTHFR mutations. I would […]

Natural approaches to treating and curing epilepsy, and an expose of just how horrible the pharmaceutical anti-epilepsy drugs are.

Over the last two decades, there has been a rapid expansion in the number and types of available antiepileptic drugs (AEDs), but there is increasing concern amongst parents and carers about their unwanted side effects. Seizure control is achieved in approximately ...

Nitrous oxide side effects are real. Learn how nitrous oxide and MTHFR may cause side effects - and why.

The most read article on MTHFR.Net is ‘Methylfolate Side Effects‘. That’s unfortunate. Avoiding side effects caused by methylfolate is ideal. It’s time I address it. How do we reduce the likelihood of methylfolate side effects? My experience has taught me these preventative measures. Before, I used to just give people methylfolate if they were found […]

Besides vaccines, increasing evidence points to diet and allergies as a cause of epilepsy. (See Alternatives, p 9, for the evidence linking this condition with allergies, particularly to gluten-c &…

Evidence of a new principle for how epigenetic changes can occur has now been outlined by a team of researchers. The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

Researchers have identified special regions of the genome where a blood sample can be used to infer epigenetic regulation throughout the body, allowing scientists to test for epigenetic causes of disease.

A new article explains that RNA also has its own spelling and grammar, just like DNA. These 'epigenetics of RNA' are called epitranscriptome.

Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ DESCRIPTION: What pregnant women eat may even affect the health of their grandchildren. Epigenetics is the science of altering the expression of your genes. No matter your family history, some genes can be effectively turned on and off by the lifestyle choices you make. See, for example: • The Alzheimer’s Gene: Controlling ApoE (http://nutritionfacts.org/video/the-alzheimers-gene-controlling-apoe/) • BRCA Breast Cancer Genes and Soy (http://nutritionfacts.org/video/brca-breast-cancer-genes-and-soy/) • Cancer Reversal Through Diet? (http://nutritionfacts.org/video/cancer-reversal-through-diet/) For more on “obesogenic” chemicals, see: • How to Avoid the Obesity-Related Plastic Chemical BPA (http://nutritionfacts.org/video/how-to-avoid-the-obesity-related-plastic-chemical-bpa) • Why is Meat a Risk Factor for Diabetes? (http://nutritionfacts.org/video/why-is-meat-a-risk-factor-for-diabetes/) • Obesity-Causing Pollutants in Food (http://nutritionfacts.org/video/obesity-causing-pollutants-in-food/) I previously touched on PAHs in Meat Fumes: Dietary Secondhand Smoke (http://nutritionfacts.org/video/meat-fumes-dietary-secondhand-smoke/). Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/animal-protein-pregnancy-and-childhood-obesity and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/animal-protein-pregnancy-and-childhood-obesity. You’ll also find a transcript of the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Image Credit: e_monk via fickr and Peter Trimming via geograph.org.uk https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

Environmental influences, including diet and exposure to toxins, clearly influence the gene expression of future generations.