Nutrition & the Epigenome
Nutrition and the Epigenome
Confirmed Anew Cow Milk May Trigger Type 1 Diabetes GreenMedInfo
For quite some time the link between juvenile onset diabetes (type 1) and cow’s milk consumption has been noted in the scientific literature. You can view 12 such references on our Cow’s Milk Page. In genetically susceptible individuals the consumption of cow’s milk triggers an autoimmune destruction of the beta-cells in the pancreas which produce insulin.
Obesity reprograms muscle stem cells -- ScienceDaily
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research.
Diabetes - Dr. Rath Research Institute
The Dr. Rath Research Institute is a non-profit organization dedicated to research and education in natural health worldwide.
Curing Painful Diabetic Neuropathy - YouTube
Diabetics suffering from nerve pain for years and then cured within days with a plant-based diet.
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What about reversing diabetic vision loss? See: Can Diabetic Retinopathy Be Reversed? (http://nutritionfacts.org/video/can-diabetic-retinopathy-be-reversed)
Just thought trans fats were in partially hydrogenated junk food? See: Trans Fat In Meat And Dairy (http://nutritionfacts.org/video/trans-fat-in-meat-and-dairy/). Ideally we’d reduce our intake as low as possible (Trans Fat, Saturated Fat, and Cholesterol: Tolerable Upper Intake of Zero http://nutritionfacts.org/video/trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero/).
The best way to prevent diabetic complications is to prevent the diabetes in the first place:
• What Causes Insulin Resistance? (http://nutritionfacts.org/what-causes-insulin-resistance)
• The Spillover Effect Links Obesity to Diabetes (http://nutritionfacts.org/video/the-spillover-effect-links-obesity-to-diabetes)
• Lipotoxicity: How Saturated Fat Raises Blood Sugar (http://nutritionfacts.org/video/lipotoxicity-how-saturated-fat-raises-blood-sugar)
• Diabetes as a Disease of Fat Toxicity (http://nutritionfacts.org/video/Diabetes-as-a-Disease-of-Fat-Toxicity)
• What Causes Diabetes? (http://nutritionfacts.org/video/what-causes-diabetes)
• Plant-Based Diets and Diabetes (http://nutritionfacts.org/video/Plant-Based-Diets-and-Diabetes)
• Plant-Based Diets for Diabetes (http://nutritionfacts.org/video/plant-based-diets-for-diabetes)
And then to reverse it:
• Reversing Diabetes with Surgery (http://nutritionfacts.org/video/reversing-diabetes-with-surgery)
• Reversing Diabetes with Food (http://nutritionfacts.org/video/reversing-diabetes-with-food)
• Diabetes Reversal: Is it the Calories or the Food? (http://nutritionfacts.org/video/13.diabetes-reversal-is-it-the-calories-or-the-food)
Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/curing-painful-diabetic-neuropathy and he'll try to answer it!
Image Credits: Alexis via Pixabay.
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Offspring may inherit legacy of their father's Toxoplasma infection -- ScienceDaily
Researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior. Studying mice infected with the common parasite Toxoplasma, the team discovered that sperm of infected fathers carried an altered 'epigenetic' signature which impacted the brains of resulting offspring. Molecules in the sperm called 'small RNA' appeared to influence the offspring's brain development and behavior.
Overweight affects DNA methylation -- ScienceDaily
The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA, concludes a large-scale international study. The study shows that a high BMI leads to epigenetic changes at nearly 200 loci of the genome – with effects on gene expression.
Parental diet affects sperm and health of future offspring -- ScienceDaily
When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team has identified a key player and the molecular events underlying this phenomenon in mice.
Can Vinegar Help with Blood Sugar Control - YouTube
The consumption of vinegar with meals was used as a folk remedy for diabetes before drugs came along, but it wasn’t put to the test until recently.
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Are these videos chock full of info or what? This is a consequence of everyone’s kind support (https://nutritionfacts.org/donate/), enabling me to hire more than a dozen researchers to help me plow through the literature. I’m embarrassed to even look at some of the videos I did years ago. They’re so one-dimensional. I’m so grateful so many of you were able to see the potential and help NutritionFacts.org become what it is today. Onward and upward!
What’s that about belly fat being reduced? You must have missed the first video in this vinegar series, Does Apple Cider Vinegar Help with Weight Loss? (http://nutritionfacts.org/video/does-apple-cider-vinegar-help-with-weight-loss)
I then covered Vinegar and Artery Function (http://nutritionfacts.org/video/vinegar-and-artery-function) and will end with Optimal Vinegar Dose (http://nutritionfacts.org/video/optimal-vinegar-dose) and Vinegar Mechanisms and Side Effects (http://nutritionfacts.org/video/vinegar-mechanisms-and-side-effects).
Did I say reverse diabetes? Reverse heart disease? See, for example, Diabetes Reversal: Is it the Calories or the Food? (http://nutritionfacts.org/video/vinegar-mechanisms-and-side-effects) and Evidence-Based Medicine or Evidence-Biased? (http://nutritionfacts.org/video/evidence-based-medicine-or-evidence-biased/)
Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/can-vinegar-help-with-blood-sugar-control and he'll try to answer it!
Image Credit: Daniel Lobo via Flickr.
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Paternal transmission of epigenetic memory via sperm -- ScienceDaily
Studies of human populations and animal models suggest that a father's experiences such as diet or environmental stress can influence the health and development of his descendants. How these effects are transmitted across generations, however, remains mysterious. A new study in the roundworm C. elegans documents the transmission via sperm of epigenetic marks that are both necessary and sufficient to guide proper development of germ cells in the offspring.
Plant-Derived Exosomes as Cross-Species Messengers and Beacons of
Cross-talk between plant and animal cells may be accomplished via microRNA-carrying exosomes, gene-regulating elements contained in plants which reinforce that food is information and suggests an inextricable co-evolutionary relationship between these two disparate kingdoms
Cause of inflammation in diabetes identified -- ScienceDaily
Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers have discovered, in mice, that when certain immune cells can’t manufacture fat, the mice don’t develop diabetes and inflammation, even when consuming a high-fat diet.
Can Diabetic Retinopathy Be Reversed NutritionFacts.org
The reversal of blindness due to hypertension and diabetes with Dr. Kempner’s rice and fruit diet demonstrates the power of diet to exceed the benefits of the best modern medicine and surgery have to offer.
Prenatal infection may alter brain development via epigenetic changes (...)
Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery. Scientists have now used a mouse model to show that activation of the mother's immune system may cause long-term alterations in the programming of the offspring's genome, known as epigenetic modifications, which lead to behavioral abnormalities in adulthood.
Prenatal infection may alter brain development via epigenetic changes -- ScienceDaily
Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery. Scientists have now used a mouse model to show that activation of the mother's immune system may cause long-term alterations in the programming of the offspring's genome, known as epigenetic modifications, which lead to behavioral abnormalities in adulthood.
Researchers solve a mystery of early embryonic development -- ScienceD (...)
A novel technique has been created to map specific chemical (or “epigenetic”) modifications made to the protein packaging of DNA using a small population of cells. Such epigenetic marks play a central role in the regulation of the genome’s expression.
Diabetes Cure in 72 hrs - 3 Days Residential Tour (English Subtitles) (...)
Cinnamon Reduces Blood Pressure, Heart Disease, Diabetes (Video) Heal Naturally
Blueberries for a Diabetic Diet and DNA Repair - YouTube
Blueberries are put to the test against insulin resistance, oxidation, and DNA damage.
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Berries pack such a nutritional punch that I recommend eating at least ½ cup a day in my Daily Dozen Checklist (http://nutritionfacts.org/video/dr-gregers-daily-dozen-checklist) (download the free iPhone (https://itunes.apple.com/us/app/dr.-gregers-daily-dozen/id1060700802?mt=8) or Android app (https://play.google.com/store/apps/details?id=org.nutritionfacts.dailydozen), or print the checklist here (https://nutritionfacts.org/daily-dozen-challenge/)).
More benefits of blueberries include:
• The Benefits of Acai vs. Blueberries for Artery Function (http://nutritionfacts.org/video/The-Benefits-of-Acai-vs-Blueberries-for-Artery-Function)
• Benefits of Blueberries for Artery Function (https://nutritionfacts.org/video/benefits-of-blueberries-for-artery-function/)
• Benefits of Blueberries for Blood Pressure May Be Blocked by Yogurt (http://nutritionfacts.org/video/Benefits-of-Blueberries-for-Blood-Pressure-May-Be-Blocked-by-yogurt)
• Benefits of Blueberries for the Brain (http://nutritionfacts.org/video/benefits-of-blueberries-for-the-brain)
• Benefits of Blueberries for Mood and Mobility (http://nutritionfacts.org/video/benefits-of-blueberries-for-mood-and-mobility)
• Best Brain Foods: Berries and Nuts Put to the Test (http://nutritionfacts.org/video/Best-Brain-Foods-Berries-and-Nuts-Put-to-the-Test)
• Benefits of Blueberries for Heart Disease (http://nutritionfacts.org/video/benefits-of-blueberries-for-heart-disease)
What else may protect against or repair DNA damage? See:
• DNA Protection from Broccoli (https://nutritionfacts.org/video/dna-protection-from-broccoli/)
• Antimutagenic Activity of Green Versus White Tea (https://nutritionfacts.org/video/antimutagenic-activity-of-green-versus-white-tea/)
• Kiwifruit and DNA Repair (https://nutritionfacts.org/video/kiwifruit-and-dna-repair/)
• Spicing Up DNA Protection (https://nutritionfacts.org/video/spicing-up-dna-protection/)
• Carcinogen Blocking Effects of Turmeric (https://nutritionfacts.org/video/carcinogen-blocking-effects-of-turmeric/)
Type 2 diabetes is caused by insulin resistance, but What Causes Insulin Resistance? (https://nutritionfacts.org/what-causes-insulin-resistance) Check out the video. And How May Plants Protect Against Diabetes? (https://nutritionfacts.org/video/how-may-plants-protect-against-diabetes/) See also Plant-Based Diets for Diabetes (https://nutritionfacts.org/video/plant-based-diets-for-diabetes), and my overview video How Not to Die from Diabetes (https://nutritionfacts.org/video/how-not-to-die-from-diabetes/).
Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/blueberries-for-a-diabetic-diet-and-dna-repair and someone on the NutritionFacts.org team will try to answer it.
Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/blueberries-for-a-diabetic-diet-and-dna-repair. You’ll also find a transcript and acknowledgments for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics.
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Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM
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Scientists create 'epigenetic couch potato' mouse -- ScienceDaily
A study in mice shows for the first time that epigenetics -- the molecular mechanisms that determine which genes are turned on or off -- plays a key role in determining an individual's innate drive to exercise.
Scientists develop technique to reveal epigenetic features of cells in the brain -- ScienceDaily
Researchers combined two different analysis techniques into one method, to simultaneously analyze how chromosomes, along with their epigenetic features, are compacted inside of single human brain cells. The method, called single-nucleus methyl-3C sequencing, not only enabled them to identify gene regulatory elements in distinct cell types, but also paves the way toward a new understanding of how some cells become dysregulated to cause disease.
Seeing cell to cell differences for first time explains symptoms of ra (...)
Every cell in the body has two genomes, one from the mother and one from the father. Until now, researchers have lacked the tools to examine -- in a single cell -the exact readout from each genome to make RNA. Using a new technology that allows researchers to do just that, an interdisciplinary team examined a rare disease in which these two genomes are expressed differently throughout the body, even sometimes in the same organ.
Bicarbonate Supplementation Slows Progression of CKD and Improves Nutr (...)
Bicarbonate supplementation preserves renal function in experimental chronic kidney disease (CKD), but whether the same benefit occurs in humans is unknown. Here, we randomly assigned 134 adult patients with CKD (creatinine clearance [CrCl] 15 to 30 ml/min ...
Social adversity early in life may affect the expression of stress-rel (...)
New research suggests that early severe social deprivation may impact DNA modifications that affect the expression of stress-related genes.
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Berberine Helps to Balance Blood Sugar NaturalHealth365
Studies raise questions over how epigenetic information is inherited -- ScienceDaily
Evidence has been building in recent years that our diet, our habits or traumatic experiences can have consequences for the health of our children -- and even our grandchildren. The explanation that has gained most currency for how this occurs is so-called 'epigenetic inheritance' -- patterns of chemical 'marks' on or around our DNA that are hypothesized to be passed down the generations. New research suggests this mechanism of non-genetic inheritance is likely to be very rare.
Switching DNA functions on and off by means of light Biochemists use protein engineering to transfer photocaging groups to DNA -- ScienceDaily
Biochemists have developed a new strategy for controlling the biological functions of DNA (deoxyribonucleic acid) by means of light and therefore provide a tool to investigate processes which take place in cells.