N-acetyl-cysteine in the treatment of Parkinson’s disease. What are we waiting for? - ScienceDirect
Parkinson’s disease is an age-related neurodegenerative disorder that is ameliorated with levodopa. However, long-term use of this drug is limited by …
Mechanisms of Laminaria japonica Polysaccharide Digestion and Absorption: Structure, In Vivo Fluorescence Imaging, and Gut Microbiota | Journal of Agricultural and Food Chemistry
This study clarified the structure and digestive properties of the Laminaria japonica polysaccharide (LJP). It was demonstrated that LJP belongs to a heteropolysaccharide composed of mannuronic acid, fucose, galactose, glucuronic acid, mannose, xylose, glucose, and guluronic acid in the proportion of 34.56%: 30.55%: 10.63%: 7.52%: 6.66%: 3.74%: 3.62%: 2.72%, with a backbone chain composed of →4)-β-d-ManA-(1→, →3)-α-l-Fucp-(1→, →4)-α-GulA-(1→, →3,4)-α-GlcA-(1→, and →4)-β-d-GlcA-(1→. In vivo fluorescence imaging indicated that LJP was mainly distributed in the stomach and intestinal segments of mice, and the fluorescence signal gradually disappeared after 12 h of digestion. In addition, LJP had no effect on the phenotype and general health of mice while promoting the proliferation of the beneficial bacteria Rikenella, Rikenellaceae_RC9_gut_group. Notably, 100 mg/kg LJP significantly increased the levels of acetic and butyric acid in the mice feces, which were 1.51 and 2.65 folds higher than the controls, respectively. Our study illuminated the absorption and distribution mechanism of LJP, providing a scientific reference for revealing LJP as a potential prebiotic.
BEWARE: They’re Trying to Fool You With This SHADY Practice - YouTube
Scientific fraud is on the rise. In this episode of Answers News, our hosts Bryan Osborne, Avery Foley, and Dr. Brian Thomas share their perspectives on this...
I Got ChatGPT To Admit Its Antichrist Purpose... - YouTube
ChatGPT Just Admitted Its Antichrist Purpose...They said it was just a tool… but what if it’s part of something much darker? In this video, I confront ChatGP...
Healthy water creates the structure, solidity and circulation throughout the body and plays a critical role in preventing many common "inexplicable" diseases.
JUST RELEASED: The NOW Prophecies Are Coming To Pass - YouTube
This is a vintage conference message by Bill Salus delivered in 2018, but has just now been released on YouTube by the host ministry called, Here the Watchme...
Stevia Kills Lyme Disease Pathogen Better Than Antibiotics
Lyme disease is exceedingly difficult to treat, due to its well-known shape-shifting (pleomorphic) abilities, with conventional antibiotics often failing to produce a long-term cure. Could the commonly used natural plant stevia provide a safer, and more effective means to combat this increasingly prevalent infection?
Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illnesses - PubMed
Around 10-20% of people who contract Lyme disease, the most common tickborne disease in the U.S., develop persistent, often debilitating symptoms such as chronic pain, fatigue, and cognitive dysfunction. Lyme infection-associated chronic illnesses (IACI) share symptoms common to other IACI such as L …
Lyme disease and the pursuit of a clinical cure - PMC
Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne illness in the United States. Many aspects of the disease are still topics of controversy within the scientific and medical communities. One particular ...
PhosChol PPC is the #1 healthcare professional brand of pharmaceutical grade polyenyl-phosphatidylcholine (PPC). Over 200 million doses have been administered by doctors in the United States alone. PhosChol is the highest concentrated source of active ingredient and is the Gold Standard PC for purity, and results.
WHISTLEBLOWER: July "Practice" Red Heifer Ceremony was ACTUALLY REAL!! - YouTube
A whistleblower reports that July's Red Heifer "Trial Run" was actually REAL! And that the Red Heifer was 100% perfect. Click here to watch this explosive Ne...
Jonathan Cahn Answers Candace Owens & Varied Anti-Semites | Jonathan Cahn Prophetic - YouTube
What happened to Candace Owens? Something dark. Jonathan Cahn addresses it, the charges she’s levelled against the Jewish people, and even the rise of antis...
Repurposed Drugs in Oncology: Current State Of The Evidence And A Case Series In Metastatic Lung Cancer
A review of the existing evidence base for repurposing drugs to treat cancer, followed by a case series of five consecutive patients treated with combination repurposed drug protocols.
Progress in the Study of Fucoidan Degradation - ScienceDirect
Fucoidan, a sulfated polysaccharide, demonstrates many biological activities. It has found extensive applications across medicine, food, cosmetics, an…
Soybean polyenylphosphatidylcholine (PPC) is beneficial in liver and extrahepatic tissue injury: An update in experimental research - PubMed
Polyenylphosphatidylcholine (PPC) is a purified polyunsaturated phosphatidylcholine extract of soybeans. This article updates PPC's beneficial effects on various forms of liver cell injury and other tissues in experimental research. PPC downregulates hepatocyte CYP2E1 expression and associated hepat …
I Convinced Grok Humans Lived With Dinosaurs (Using Science) - YouTube
I used strict math, logic, and science to show Grok (Elon Musk’s AI) that humans and dinosaurs lived at the same time — it admitted it. But then, when I aske...
BREAKING NEWS | Red Heifer Update | Mondo Gonzales - YouTube
In this powerful update, Mondo Gonzales shares the latest developments on the Red Heifers. GET MONDO'S BOOK:https://prophecywatchers.com/product/new-edition-...
Neuroprotective and Anti-Inflammatory Activity of Undaria pinnatifida Fucoidan In Vivo—A Proteomic Investigation - PMC
Undaria pinnatifida fucoidan (UPF), a bioactive sulphated polysaccharide, is widely recognised for its anti-inflammatory, antioxidant, antitumor, anticoagulant, antiviral, and immunomodulatory properties. However, the precise mechanisms by which UPF ...
Anti-Inflammatory and Neuroprotective Effects of Undaria pinnatifida Fucoidan[v1] | Preprints.org
Undaria pinnatifida fucoidan (UPF), a sulphated polysaccharide derived from brown seaweed, has attracted increasing scientific interest for its wide-ranging anti-inflammatory and neuroprotective properties. Previous studies have demonstrated that UPF exerts significant anti-inflammatory effects through the downregulation of pro-inflammatory cytokines, inhibition of key signalling pathways such as NF-κB and MAPKs, suppression of oxidative stress, and modulation of immune mediators and gut microbiota. In parallel, emerging evidence highlights UPF's neuroprotective potential, characterised by reduced neuroinflammation, oxidative damage, and amyloid-beta accumulation, alongside enhanced antioxidant defence and neuronal function. Current investigations reinforce these findings, suggesting that UPF may serve as a valuable adjunct in managing inflammation-related disorders and neurodegenerative conditions.
This review summarises the current knowledge on UPF’s mechanisms of action, with a particular focus on its anti-inflammatory and neuroprotective pathways and implications for brain health, while also identifying gaps for future research and clinical translation.