2016

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Mechanisms of Laminaria japonica Polysaccharide Digestion and Absorption: Structure, In Vivo Fluorescence Imaging, and Gut Microbiota | Journal of Agricultural and Food Chemistry
Mechanisms of Laminaria japonica Polysaccharide Digestion and Absorption: Structure, In Vivo Fluorescence Imaging, and Gut Microbiota | Journal of Agricultural and Food Chemistry
This study clarified the structure and digestive properties of the Laminaria japonica polysaccharide (LJP). It was demonstrated that LJP belongs to a heteropolysaccharide composed of mannuronic acid, fucose, galactose, glucuronic acid, mannose, xylose, glucose, and guluronic acid in the proportion of 34.56%: 30.55%: 10.63%: 7.52%: 6.66%: 3.74%: 3.62%: 2.72%, with a backbone chain composed of →4)-β-d-ManA-(1→, →3)-α-l-Fucp-(1→, →4)-α-GulA-(1→, →3,4)-α-GlcA-(1→, and →4)-β-d-GlcA-(1→. In vivo fluorescence imaging indicated that LJP was mainly distributed in the stomach and intestinal segments of mice, and the fluorescence signal gradually disappeared after 12 h of digestion. In addition, LJP had no effect on the phenotype and general health of mice while promoting the proliferation of the beneficial bacteria Rikenella, Rikenellaceae_RC9_gut_group. Notably, 100 mg/kg LJP significantly increased the levels of acetic and butyric acid in the mice feces, which were 1.51 and 2.65 folds higher than the controls, respectively. Our study illuminated the absorption and distribution mechanism of LJP, providing a scientific reference for revealing LJP as a potential prebiotic.
·pubs.acs.org·
Mechanisms of Laminaria japonica Polysaccharide Digestion and Absorption: Structure, In Vivo Fluorescence Imaging, and Gut Microbiota | Journal of Agricultural and Food Chemistry
I Got ChatGPT To Admit Its Antichrist Purpose... - YouTube
I Got ChatGPT To Admit Its Antichrist Purpose... - YouTube
ChatGPT Just Admitted Its Antichrist Purpose...They said it was just a tool… but what if it’s part of something much darker? In this video, I confront ChatGP...
·youtube.com·
I Got ChatGPT To Admit Its Antichrist Purpose... - YouTube
The Hidden Powers of Water That Shape Our Health
The Hidden Powers of Water That Shape Our Health
Healthy water creates the structure, solidity and circulation throughout the body and plays a critical role in preventing many common "inexplicable" diseases.
·midwesterndoctor.com·
The Hidden Powers of Water That Shape Our Health
Stevia Kills Lyme Disease Pathogen Better Than Antibiotics
Stevia Kills Lyme Disease Pathogen Better Than Antibiotics
Lyme disease is exceedingly difficult to treat, due to its well-known shape-shifting (pleomorphic) abilities, with conventional antibiotics often failing to produce a long-term cure. Could the commonly used natural plant stevia provide a safer, and more effective means to combat this increasingly prevalent infection?
·greenmedinfo.com·
Stevia Kills Lyme Disease Pathogen Better Than Antibiotics
Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illnesses - PubMed
Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illnesses - PubMed
Around 10-20% of people who contract Lyme disease, the most common tickborne disease in the U.S., develop persistent, often debilitating symptoms such as chronic pain, fatigue, and cognitive dysfunction. Lyme infection-associated chronic illnesses (IACI) share symptoms common to other IACI such as L …
·pubmed.ncbi.nlm.nih.gov·
Charting a Path Toward New Treatments for Lyme Infection-Associated Chronic Illnesses - PubMed
Lyme disease and the pursuit of a clinical cure - PMC
Lyme disease and the pursuit of a clinical cure - PMC
Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne illness in the United States. Many aspects of the disease are still topics of controversy within the scientific and medical communities. One particular ...
·pmc.ncbi.nlm.nih.gov·
Lyme disease and the pursuit of a clinical cure - PMC
PhosChol PPC
PhosChol PPC
PhosChol PPC is the #1 healthcare professional brand of pharmaceutical grade polyenyl-phosphatidylcholine (PPC). Over 200 million doses have been administered by doctors in the United States alone. PhosChol is the highest concentrated source of active ingredient and is the Gold Standard PC for purity, and results.
·nutrasal.com·
PhosChol PPC
Soybean polyenylphosphatidylcholine (PPC) is beneficial in liver and extrahepatic tissue injury: An update in experimental research - PubMed
Soybean polyenylphosphatidylcholine (PPC) is beneficial in liver and extrahepatic tissue injury: An update in experimental research - PubMed
Polyenylphosphatidylcholine (PPC) is a purified polyunsaturated phosphatidylcholine extract of soybeans. This article updates PPC's beneficial effects on various forms of liver cell injury and other tissues in experimental research. PPC downregulates hepatocyte CYP2E1 expression and associated hepat …
·pubmed.ncbi.nlm.nih.gov·
Soybean polyenylphosphatidylcholine (PPC) is beneficial in liver and extrahepatic tissue injury: An update in experimental research - PubMed
Build Apps with AI in Minutes | Base44
Build Apps with AI in Minutes | Base44
From idea to live app in minutes. Base44 gives you the tools to launch fully-functional apps - no code, no setup, no hassle.
·base44.com·
Build Apps with AI in Minutes | Base44
Neuroprotective and Anti-Inflammatory Activity of Undaria pinnatifida Fucoidan In Vivo—A Proteomic Investigation - PMC
Neuroprotective and Anti-Inflammatory Activity of Undaria pinnatifida Fucoidan In Vivo—A Proteomic Investigation - PMC
Undaria pinnatifida fucoidan (UPF), a bioactive sulphated polysaccharide, is widely recognised for its anti-inflammatory, antioxidant, antitumor, anticoagulant, antiviral, and immunomodulatory properties. However, the precise mechanisms by which UPF ...
·pmc.ncbi.nlm.nih.gov·
Neuroprotective and Anti-Inflammatory Activity of Undaria pinnatifida Fucoidan In Vivo—A Proteomic Investigation - PMC
Anti-Inflammatory and Neuroprotective Effects of Undaria pinnatifida Fucoidan[v1] | Preprints.org
Anti-Inflammatory and Neuroprotective Effects of Undaria pinnatifida Fucoidan[v1] | Preprints.org
Undaria pinnatifida fucoidan (UPF), a sulphated polysaccharide derived from brown seaweed, has attracted increasing scientific interest for its wide-ranging anti-inflammatory and neuroprotective properties. Previous studies have demonstrated that UPF exerts significant anti-inflammatory effects through the downregulation of pro-inflammatory cytokines, inhibition of key signalling pathways such as NF-κB and MAPKs, suppression of oxidative stress, and modulation of immune mediators and gut microbiota. In parallel, emerging evidence highlights UPF's neuroprotective potential, characterised by reduced neuroinflammation, oxidative damage, and amyloid-beta accumulation, alongside enhanced antioxidant defence and neuronal function. Current investigations reinforce these findings, suggesting that UPF may serve as a valuable adjunct in managing inflammation-related disorders and neurodegenerative conditions. This review summarises the current knowledge on UPF’s mechanisms of action, with a particular focus on its anti-inflammatory and neuroprotective pathways and implications for brain health, while also identifying gaps for future research and clinical translation.
·preprints.org·
Anti-Inflammatory and Neuroprotective Effects of Undaria pinnatifida Fucoidan[v1] | Preprints.org