2016

In patients with long-term type 1 diabetes, the tuberculosis vaccine BCG lowers blood sugar levels to near-normal after three years. Denise Faustman and her team from Massachusetts General Hospital and Harvard Medical School investigated a cohort of type 1 diabetics that received two doses of BCG before being monitored over eight years. After three years, vaccine-treated patients lowered their HbA1c levels—a diabetes biomarker reflecting average blood sugar over 8–12 weeks—by over 10%. This reduction increased to 18% in the fourth year, after which HbA1c levels remained low up to the final year of monitoring. The researchers report that the BCG vaccine appeared to reset diabetes-implicated parts of the immune system and, through a novel mechanism, shift glucose metabolism to lower blood sugar to healthy levels. Future studies will further classify BCG’s benefits in diabetes.

The bacillus Calmette-Guérin (BCG) vaccine is the only licensed vaccine for human use against tuberculosis (TB). Although controversy exists about its efficacy, the BCG vaccine is able to protect newborns and children against disseminated forms ...

The delivery route and dose of the BCG vaccine profoundly alters the protective outcome after Mycobacterium tuberculosis challenge in non-human primates.

Repeat BCG Vaccinations for the Treatment of Established Type 1 Diabetes - Full Text View.

It costs more than $1.7 million to prevent just one additional case of active tuberculosis in a health care worker. Experts say there's a better way.

The bacillus Calmette-Guérin (BCG) vaccine is one of the oldest vaccines in history and has been investigated as a potential treatment for type 1 diabetes by Dr. Denise Faustman and her team at the Massachusetts General Hospital (MGH) for over a decade. A new study published today in npj Vaccines describes the long-term outcomes of BCG administration to patients with type 1 diabetes. The study enrolled 282 individuals, 52 of whom received the vaccine. The average age of type 1 diabetes duration among the cohort was 19 years. The patients were followed for over eight years, and their A1c levels were evaluated. The study reports that patients with type 1 diabetes who received just two doses of the BCG vaccine, spaced four weeks apart, achieved markedly lower A1c levels compared to the control group. This result was observed three years after the vaccine administration and continued for the next five years […]

How do you start a keto or low-carb diet? We have delicious recipes, amazing meal plans, the best keto videos, and a supportive low-carb community to help dramatically improve your health. Welcome to Diet Doctor, where we make low carb simple.

A study published in Pediatrics suggests a low carb diet helps children with diabetes maintain stable blood sugar levels.

2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FL Management of Type 1 Diabetes with a Ketogenic Diet Presented by: Keith Runyan, M.D. This video is for informational purposes only. It should not be taken as medical advice.

My personal experience with managing my type 1 diabetes with a ketogenic diet and exercise

Listen to Dr Carrie Diulus, US board-certified orthopaedic spinal surgeon and a thriving type 1 diabetic explain how she uses the vegan ketogenic diet and insulin strategies to manage her diabetes. This episode is great for type 1 diabetics or vegan/vegetarians wondering if low carb/keto diets could work for them.

Undoubtedly, food intake and blood glucose levels are intimately connected, and diet plays a central role in post-prandial blood glucose levels. There is much debate about diet when it comes to managing type 1 diabetes. While many have found success with a low-carbohydrate approach, the diet remains controversial. In particular, little research has been conducted on the use of a low-carbohydrate approach for the management of type 1 diabetes in children. A new study, published today in the journal Pediatrics, examined the effects of a very low-carbohydrate diet on glycemic control and adverse events in a cohort of adults and children with type 1 diabetes. Overall, the research demonstrated that the study participants experienced dramatic improvements in HbA1c levels, with remarkable glucose stability, and a low rate of adverse events when following a low-carbohydrate approach. Study Design The survey-based study was funded by the National Institute of Diabetes and Digestive […]

I am a retired physician living with Type 1 diabetes since 1998. I follow a ketogenic diet for diabetes management, and maintain nutritional ketosis. I participate in endurance sports.

Sodium bicarbonate is a natural compound found throughout nature—in the ocean, in the soil, in our foods, and in our bodies. Baking soda is a neutralizer of many other compounds, which makes it extremely helpful as a medicine in this age of toxicity that we are all presently passing through. Its backbone characteristic is to... View Article

48 Surprising Facts About Gluten - In this research breakdown from the Gluten Free Society, 48 scientifically researched, yet little known...

Sodium bicarbonate is an excellent agent for a natural alkaline approach in the treatment for all sickness and disease, including cancer.  S...

Kidney failure is painful and often avoidable. Know these 10 symptoms of kidney failure to watch out for, and 9 tips for good kidney health.

Background: Intensive care units (ICUs) admissions due to sepsis represent 2 to 11%. Although there are well stablished  therapeutic available, it still is the major cause of death in most ICUs and the leading cause of acute kidney injury. The objective of this work was to evaluate the role of Aloe vera extract on survival rates and kidney histopathology of mice submitted to sepsis induced by cecal ligation and puncture. Methods and Findings: Twenty six mice were distributed into four groups: Sham - surgery simulation (N=5); Control - Cecal ligation and puncture was performed (N=7); Aloe - Surgery simulation and treatment with Aloe vera extract (N=7); and Sepsis + Aloe - Cecal ligation and puncture was performed followed by treatment with Aloe vera extract (N=7). The animals were observed until death. Kidneys were analysed by histopathology. Kruskall-Wallis test was used to compare the histopathological results. Survival analysis was assessed by Kaplan-Meier statistics and compared using log rank test. A significance level of 5% was adopted. The survival time ranged from 19 hours for the Control group up to 24 hours for the animals of Sepsis + Aloe group, corresponding to a survival time of 1.26 times greater (p0.05). Conclusions: Aloe vera extracts delays mortality but does not attenuate kidney injury in sepsis induced by cecal ligation and puncture in mice.